a3ar agonist cf102 Search Results


a 3 ar agonist cf102  (Can Fite Biopharma)
90
Can Fite Biopharma a 3 ar agonist cf102
A 3 Ar Agonist Cf102, supplied by Can Fite Biopharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a3ar+agonist+cf102/cf102/pmc03415694-163-6-0
Average 90 stars, based on 1 article reviews
a 3 ar agonist cf102 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
a3ar agonist 2 cl ib meca  (Tocris)
92
Tocris a3ar agonist 2 cl ib meca
(A) IF was performed using DAPI to counterstain the nuclei and a specific antibody to label <t>A3AR</t> proteins. The strong green fluorescence signal indicating A3AR was observed mainly in the colonic crypt epithelial cells. The expression of A3AR was reduced in DSS colitis mice. Treatment with 2-Cl-IB-MECA showed no obvious effect on A3AR expression. A3AR mRNA (B) and protein (C) expression in colonic epithelial cells were measured by qRT-PCR and western blot, respectively. Compared with the normal group, the mRNA and protein expression levels of A3AR significantly decreased after DSS induction of colitis (* P < 0.01) and showed no significant alterations among the other three groups including DSS, DMSO, and 2-Cl-IB-MECA groups ( P > 0.05). Data are shown as mean ± SD. The blots in panel C were performed under the same experimental condition except for blotting with the different antibodies, respectively. These blots were shown as cropped images.
A3ar Agonist 2 Cl Ib Meca, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a3ar+agonist+cf102/2-Cl-IB-MECA/pmc04357005-106-2-12
Average 92 stars, based on 1 article reviews
a3ar agonist 2 cl ib meca - by Bioz Stars, 2026-10
92/100 stars
  Buy from Supplier
a 3 ar agonist cf 102  (Can Fite Biopharma)
90
Can Fite Biopharma a 3 ar agonist cf 102
(A) IF was performed using DAPI to counterstain the nuclei and a specific antibody to label <t>A3AR</t> proteins. The strong green fluorescence signal indicating A3AR was observed mainly in the colonic crypt epithelial cells. The expression of A3AR was reduced in DSS colitis mice. Treatment with 2-Cl-IB-MECA showed no obvious effect on A3AR expression. A3AR mRNA (B) and protein (C) expression in colonic epithelial cells were measured by qRT-PCR and western blot, respectively. Compared with the normal group, the mRNA and protein expression levels of A3AR significantly decreased after DSS induction of colitis (* P < 0.01) and showed no significant alterations among the other three groups including DSS, DMSO, and 2-Cl-IB-MECA groups ( P > 0.05). Data are shown as mean ± SD. The blots in panel C were performed under the same experimental condition except for blotting with the different antibodies, respectively. These blots were shown as cropped images.
A 3 Ar Agonist Cf 102, supplied by Can Fite Biopharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a3ar+agonist+cf102/cf101/pmc02579661-207-7-22
Average 90 stars, based on 1 article reviews
a 3 ar agonist cf 102 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
2-chloro-n6-(3-iodobenzyl)-adenosine-5′-n-methyluronamide cl-ib-meca  (Can Fite Biopharma)
90
Can Fite Biopharma 2-chloro-n6-(3-iodobenzyl)-adenosine-5′-n-methyluronamide cl-ib-meca
(A) IF was performed using DAPI to counterstain the nuclei and a specific antibody to label <t>A3AR</t> proteins. The strong green fluorescence signal indicating A3AR was observed mainly in the colonic crypt epithelial cells. The expression of A3AR was reduced in DSS colitis mice. Treatment with 2-Cl-IB-MECA showed no obvious effect on A3AR expression. A3AR mRNA (B) and protein (C) expression in colonic epithelial cells were measured by qRT-PCR and western blot, respectively. Compared with the normal group, the mRNA and protein expression levels of A3AR significantly decreased after DSS induction of colitis (* P < 0.01) and showed no significant alterations among the other three groups including DSS, DMSO, and 2-Cl-IB-MECA groups ( P > 0.05). Data are shown as mean ± SD. The blots in panel C were performed under the same experimental condition except for blotting with the different antibodies, respectively. These blots were shown as cropped images.
2 Chloro N6 (3 Iodobenzyl) Adenosine 5′ N Methyluronamide Cl Ib Meca, supplied by Can Fite Biopharma, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a3ar+agonist+cf102/n6+benzyladenosine+5++n+methyluronamides/us11291681-176-1-16
Average 90 stars, based on 1 article reviews
2-chloro-n6-(3-iodobenzyl)-adenosine-5′-n-methyluronamide cl-ib-meca - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
tlr agonists ana773  (Anadys Pharmaceuticals)
90
Anadys Pharmaceuticals tlr agonists ana773
(A) IF was performed using DAPI to counterstain the nuclei and a specific antibody to label <t>A3AR</t> proteins. The strong green fluorescence signal indicating A3AR was observed mainly in the colonic crypt epithelial cells. The expression of A3AR was reduced in DSS colitis mice. Treatment with 2-Cl-IB-MECA showed no obvious effect on A3AR expression. A3AR mRNA (B) and protein (C) expression in colonic epithelial cells were measured by qRT-PCR and western blot, respectively. Compared with the normal group, the mRNA and protein expression levels of A3AR significantly decreased after DSS induction of colitis (* P < 0.01) and showed no significant alterations among the other three groups including DSS, DMSO, and 2-Cl-IB-MECA groups ( P > 0.05). Data are shown as mean ± SD. The blots in panel C were performed under the same experimental condition except for blotting with the different antibodies, respectively. These blots were shown as cropped images.
Tlr Agonists Ana773, supplied by Anadys Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a3ar+agonist+cf102/ana773/us08541434-979-13-17
Average 90 stars, based on 1 article reviews
tlr agonists ana773 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
scy-635  (SCYNEXIS Inc)
90
SCYNEXIS Inc scy-635
(A) IF was performed using DAPI to counterstain the nuclei and a specific antibody to label <t>A3AR</t> proteins. The strong green fluorescence signal indicating A3AR was observed mainly in the colonic crypt epithelial cells. The expression of A3AR was reduced in DSS colitis mice. Treatment with 2-Cl-IB-MECA showed no obvious effect on A3AR expression. A3AR mRNA (B) and protein (C) expression in colonic epithelial cells were measured by qRT-PCR and western blot, respectively. Compared with the normal group, the mRNA and protein expression levels of A3AR significantly decreased after DSS induction of colitis (* P < 0.01) and showed no significant alterations among the other three groups including DSS, DMSO, and 2-Cl-IB-MECA groups ( P > 0.05). Data are shown as mean ± SD. The blots in panel C were performed under the same experimental condition except for blotting with the different antibodies, respectively. These blots were shown as cropped images.
Scy 635, supplied by SCYNEXIS Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a3ar+agonist+cf102/scy+635/us08697694-2242-90-93
Average 90 stars, based on 1 article reviews
scy-635 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier
a-831  (Arrow Therapeutics)
90
Arrow Therapeutics a-831
(A) IF was performed using DAPI to counterstain the nuclei and a specific antibody to label <t>A3AR</t> proteins. The strong green fluorescence signal indicating A3AR was observed mainly in the colonic crypt epithelial cells. The expression of A3AR was reduced in DSS colitis mice. Treatment with 2-Cl-IB-MECA showed no obvious effect on A3AR expression. A3AR mRNA (B) and protein (C) expression in colonic epithelial cells were measured by qRT-PCR and western blot, respectively. Compared with the normal group, the mRNA and protein expression levels of A3AR significantly decreased after DSS induction of colitis (* P < 0.01) and showed no significant alterations among the other three groups including DSS, DMSO, and 2-Cl-IB-MECA groups ( P > 0.05). Data are shown as mean ± SD. The blots in panel C were performed under the same experimental condition except for blotting with the different antibodies, respectively. These blots were shown as cropped images.
A 831, supplied by Arrow Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a3ar+agonist+cf102/a+831/us09433621-2547-36-48
Average 90 stars, based on 1 article reviews
a-831 - by Bioz Stars, 2026-10
90/100 stars
  Buy from Supplier

Image Search Results


(A) IF was performed using DAPI to counterstain the nuclei and a specific antibody to label A3AR proteins. The strong green fluorescence signal indicating A3AR was observed mainly in the colonic crypt epithelial cells. The expression of A3AR was reduced in DSS colitis mice. Treatment with 2-Cl-IB-MECA showed no obvious effect on A3AR expression. A3AR mRNA (B) and protein (C) expression in colonic epithelial cells were measured by qRT-PCR and western blot, respectively. Compared with the normal group, the mRNA and protein expression levels of A3AR significantly decreased after DSS induction of colitis (* P < 0.01) and showed no significant alterations among the other three groups including DSS, DMSO, and 2-Cl-IB-MECA groups ( P > 0.05). Data are shown as mean ± SD. The blots in panel C were performed under the same experimental condition except for blotting with the different antibodies, respectively. These blots were shown as cropped images.

Journal: Scientific Reports

Article Title: An adenosine A3 receptor agonist inhibits DSS-induced colitis in mice through modulation of the NF-κB signaling pathway

doi: 10.1038/srep09047

Figure Lengend Snippet: (A) IF was performed using DAPI to counterstain the nuclei and a specific antibody to label A3AR proteins. The strong green fluorescence signal indicating A3AR was observed mainly in the colonic crypt epithelial cells. The expression of A3AR was reduced in DSS colitis mice. Treatment with 2-Cl-IB-MECA showed no obvious effect on A3AR expression. A3AR mRNA (B) and protein (C) expression in colonic epithelial cells were measured by qRT-PCR and western blot, respectively. Compared with the normal group, the mRNA and protein expression levels of A3AR significantly decreased after DSS induction of colitis (* P < 0.01) and showed no significant alterations among the other three groups including DSS, DMSO, and 2-Cl-IB-MECA groups ( P > 0.05). Data are shown as mean ± SD. The blots in panel C were performed under the same experimental condition except for blotting with the different antibodies, respectively. These blots were shown as cropped images.

Article Snippet: The selective A3AR agonist 2-Cl-IB-MECA (2-Cl-IB-MECA group) (1.0 mg/kg/day in 0.2 mL) (Tocris Bioscience, United Kingdom) or 37.5% dimethyl sulfoxide (DMSO) (vehicle group) was administered to the mice intragastrically by a feeding needle once a day, starting at day 1 from colitis induction.

Techniques: Fluorescence, Expressing, Quantitative RT-PCR, Western Blot

Primers used for quantitative reverse transcription-polymerase chain reaction in this study

Journal: Scientific Reports

Article Title: An adenosine A3 receptor agonist inhibits DSS-induced colitis in mice through modulation of the NF-κB signaling pathway

doi: 10.1038/srep09047

Figure Lengend Snippet: Primers used for quantitative reverse transcription-polymerase chain reaction in this study

Article Snippet: The selective A3AR agonist 2-Cl-IB-MECA (2-Cl-IB-MECA group) (1.0 mg/kg/day in 0.2 mL) (Tocris Bioscience, United Kingdom) or 37.5% dimethyl sulfoxide (DMSO) (vehicle group) was administered to the mice intragastrically by a feeding needle once a day, starting at day 1 from colitis induction.

Techniques: Reverse Transcription Polymerase Chain Reaction